Director of Theranostics and Radiation Science

Quick Facts

• Role: Director of Theranostics and Radiation Science (senior medical physicist leadership)

• Focus: Imaging and dosimetry strategy for nuclear medicine programs

• Collaboration: Cross-functional work across imaging/radioconjugate development and clinical teams

Description

The Director, Theranostics and Radiation Science leads and develops the Radiation Sciences team and serves as a senior medical physicist supporting imaging and dosimetry strategy across programs. You will optimize nuclear medicine imaging protocols, manage patient-specific (internal) dosimetry calculations, and provide technical support to clinical sites and cross-functional stakeholders. The role includes vendor/contractor oversight and authoring/reviewing dosimetry and imaging content for regulatory submissions.

Responsibilities

• Own and execute imaging and dosimetry strategy for assigned programs, from Phase 0 biodistribution studies through clinical dose escalation

• Optimize and review nuclear medicine imaging protocols, including QC parameters, acquisition/reconstruction, radiation dose determination, and protocol dose management

• Define technical requirements for clinical-site imaging execution and ensure adherence to study protocols

• Design and oversee QC protocols with internal teams and external partners for imaging review/processing

• Manage external imaging and dosimetry vendors/contractors (scope, deliverables, issue resolution)

• Perform, review, and oversee image-based, patient-specific internal dosimetry calculations

• Author and review dosimetry and imaging content for regulatory submissions (e.g., IND/CTA) and health-authority responses

• Provide training, mentorship, and problem-solving support to Radiation Science and internal/external clinical study teams

• Represent Radiation Science on cross-functional study teams to ensure QC, acquisition, dose management, and regulatory compliance best practices

• Support regulatory compliance for radioactive materials; stay current with AAPM, SNMMI, NRC and international guidance

• Contribute to research and discovery projects as needed

• Travel as needed (5–10%)

Requirements

• Ph.D. or M.S. in medical physics, physics, or related scientific discipline (required) plus a bachelor’s degree in a physical science/engineering/math field (required)

• Medical physics residency (or equivalent postdoctoral training) and 5–10 years post-training experience in nuclear medicine, molecular imaging, or radiopharmaceutical development (1–2 years industry preferred)

• Personalized dosimetry experience for radiopharmaceuticals with OLINDA, MIM, or similar tools (required)

• SPECT and PET imaging experience, including image reconstruction and camera quality control (required)

• Strong radiation biology and radiation physics knowledge (required)

• Computer skills with DICOM and PACS; working knowledge of at least one programming language (MATLAB, R, Python) (required)

• Ability to interpret imaging-related protocol requirements and translate dosimetry/biodistribution results into program recommendations

• Experience mentoring/supervising scientific staff and leading cross-functional workstreams

• Knowledge of radioactive materials regulations and guidelines (e.g., AAPM, SNMMI, NRC)

Benefits

• Short-term incentive bonus opportunity

• Eligibility for an equity-based long-term incentive program

• 401(k) retirement plan

• Paid vacation and holidays; paid leaves

• Health benefits: medical, prescription drug, dental, and vision coverage (per plan terms)