Sr. Manager/ Associate Director, Statistical Programming

🏢 Summary: Senior Manager / Associate Director, Biostatistics role providing strategic and operational statistical leadership across clinical development programs. The position leads study design, analysis, regulatory interactions, and cross-functional collaboration to support global submissions and evidence generation. This role influences development strategy, applies advanced statistical methodologies, and oversees statistical deliverables for clinical trials and post-marketing research. 🗂️ Requirements: PhD in Biostatistics, Statistics or related quantitative field with 4–6+ years industry experience OR MS with 6–8+ years industry experience, Experience providing statistical leadership for clinical development programs and clinical trials, Strong knowledge of clinical trial methodology, study design, statistical analysis, and regulatory requirements, Experience supporting regulatory submissions and health authority interactions, Experience leading cross-functional teams, Expertise in adaptive designs, longitudinal analyses, survival analyses, integrated analyses, Experience overseeing CROs and external statistical vendors, Proficiency in SAS and/or R, Strong understanding of ICH, FDA, EMA and global regulatory guidance 📃 Skills: SAS, R, Biostatistics, Statistics, ClinicalTrials, AdaptiveDesign, LongitudinalAnalysis, SurvivalAnalysis, IntegratedAnalysis, HEOR, RealWorldEvidence, ICH, FDA, EMA 🏢 Description: Position Summary: Senior Manager / Associate Director, Biostatistics to provide strategic and operational statistical leadership across clinical development programs. This individual will serve as the lead biostatistician for one or more clinical development programs and will partner closely with Clinical Development, Medical Affairs, Data Management, Statistical Programming, Regulatory Affairs, and external partners to ensure the delivery of high-quality statistical strategy, analyses, and regulatory submissions. The successful candidate will contribute to study design, protocol development, analysis planning, interpretation of clinical data, regulatory interactions, and evidence generation activities that support development, registration, and lifecycle management of programs. This role offers the opportunity to influence development strategy, advance innovative statistical methodologies, and contribute to regulatory and business decision-making. Essential Duties and Responsibilities: Statistical Leadership & Clinical Development - Lead the biostatistics strategy for one or more clinical development programs and studies. - Serve as the statistical representative on cross-functional study teams, Clinical Development Teams, and governance committees. - Collaborate with Clinical Development and Medical teams to design clinical studies aligned with program objectives, regulatory expectations, and business needs. - Provide strategic input into clinical development plans, including study design, endpoint selection, sample size determination, interim analyses, and decision criteria. - Identify potential statistical, operational, or scientific challenges and proactively develop solutions. - Evaluate and implement innovative statistical methodologies to enhance development strategies and study efficiency. - Support quantitative decision-making, including benefit-risk assessments, probability of technical success analyses, and Go/No-Go evaluations. Study Design, Analysis & Reporting - Author and/or review statistical sections of protocols, statistical analysis plans (SAPs), data review plans, and study reports. - Develop and/or oversee analysis strategies, including tables, listings, and figures (TLFs), ensuring methodological rigor and regulatory compliance. - Ensure timely delivery and quality of statistical analyses for interim reviews, final analyses, integrated summaries, and regulatory submissions. - Interpret study results and effectively communicate findings to technical and non-technical audiences. - Prepare and review abstracts, posters, manuscripts, presentations, and scientific publications. Regulatory & External Interactions - Contribute to regulatory strategies and support global submissions. - Represent Biostatistics during interactions with health authorities, including FDA, EMA, PMDA, and other regulatory agencies, as appropriate. - Support responses to regulatory questions related to study design, analysis methodologies, and interpretation of results. - Ensure statistical deliverables meet applicable ICH, FDA, EMA, and other global regulatory requirements. Medical Affairs, HEOR & Evidence Generation - Provide statistical leadership for post-marketing studies, observational research, registry studies, real-world evidence initiatives, and outcomes research activities, as applicable. - Support evidence generation strategies that address clinical, scientific, payer, and market access objectives. - Collaborate with cross-functional partners to identify evidence gaps and develop analytical approaches to address unmet evidence needs. - Contribute statistical expertise to publications, scientific communications, and evidence dissemination activities. Vendor Oversight & Operational Excellence - Oversee CROs, functional service providers, and external statistical vendors to ensure high-quality deliverables and adherence to timelines. - Collaborate with Statistical Programming and Data Management to ensure data quality and efficient execution of analyses. - Support departmental initiatives focused on process improvement, innovation, quality standards, and inspection readiness. - Contribute to the development and maintenance of statistical standards, procedures, and best practices. Required Education and Experience: Sr Manager: - Ph.D. in Biostatistics, Statistics, or a related quantitative discipline with a minimum of 4 years of pharmaceutical, biotechnology, or clinical research experience; or M.S. with a minimum of 6 years of experience. Associate Director: - Ph.D. in Biostatistics, Statistics, or a related quantitative discipline with a minimum of 6 years of relevant pharmaceutical industry experience; or M.S. with a minimum of 8 years of experience. - Demonstrated experience providing statistical leadership for clinical development programs and clinical trials. - Strong knowledge of clinical trial methodology, study design, statistical analysis, and regulatory requirements. - Experience supporting regulatory submissions and health authority interactions. - Experience leading cross-functional teams and influencing development strategies. - Expertise in statistical methods applicable to clinical development, including adaptive designs, longitudinal analyses, survival analyses, and integrated analyses. - Experience overseeing CROs and external statistical vendors. - Proficiency in SAS and/or R. - Strong understanding of ICH, FDA, EMA, and other global regulatory guidance. - Experience with real-world evidence, observational studies, HEOR, or post-marketing research is a plus. - Experience in immunology, inflammation, autoimmune disease, or related therapeutic areas is preferred.

🏢 Summary: Leadership role overseeing clinical data management across development programs, ensuring high-quality, compliant clinical trial data from study start-up through database lock and regulatory submission. The position drives data strategy, database design, vendor oversight, PK data review, and cross-functional collaboration to support successful clinical and regulatory outcomes. Strong focus on regulatory compliance, inspection readiness, and industry data standards. 🗂️ Requirements: BS/BA in bioscience, engineering, computer science, medical or related field, 6+ years (MS) or 9+ years (BS) clinical data management experience for Senior Manager, 9+ years (MS) or 12+ years (BS) clinical data management experience for Associate Director, Experience leading data management from study start-up through database lock, Strong vendor and CRO oversight experience, Experience supporting regulatory submissions and inspection readiness, Knowledge of ICH-GCP and FDA regulations, Experience with EDC systems (e.g., Medidata Rave) 📃 Skills: EDC, Medidata, Rave, CDISC, CDASH, SDTM, MedDRA, WHODrug, ICH-GCP, FDA, 21CFRPart11, PK, UAT, SOP, GCDMP 🏢 Description: Position Summary: Senior Manager / Associate Director, Clinical Data Management to provide leadership and oversight of clinical data management activities across one or more development programs. This individual is responsible for ensuring the quality, integrity, timeliness, and regulatory compliance of clinical trial data from study start-up through database lock and submission readiness. Working closely with Clinical Operations, Clinical Development, Biostatistics, Statistical Programming, Clinical Pharmacology, Pharmacovigilance, Regulatory Affairs, Information Technology, and external partners, this role serves as the Data Management lead for assigned studies and programs, driving data strategy, vendor oversight, process excellence, and inspection readiness. Essential Duties and Responsibilities: Clinical Data Management Leadership - Lead clinical data management activities for assigned studies (especially PK trials) from protocol development through database lock and submission readiness. - Serve as primary point of contact for CROs and vendors, ensuring data delivery on time, within budget, and in compliance with ICH-GCP guidelines. - Represent Data Management on cross-functional study teams, aligning deliverables with study objectives, timelines, and regulatory requirements. - Develop and execute study-specific data management strategies to ensure high-quality, analyzable clinical trial data. - Oversee and maintain Data Management Plans (DMPs), data review plans, and study-level documentation. Database Design, Build, and Validation - Collaborate on design and review of electronic Case Report Forms (eCRFs). - Develop and review database build specifications, edit check specifications, CRF completion guidelines, and validation plans. - Lead User Acceptance Testing (UAT) and oversee database go-live readiness. - Ensure databases are designed and validated in accordance with protocol requirements, CDASH standards, and best practices. Data Review and Quality Oversight - Lead ongoing PK and clinical data review, discrepancy management, query generation, and resolution. - Establish and monitor data quality metrics to ensure accuracy, consistency, completeness, and analysis readiness. - Oversee reconciliation activities including SAEs, laboratory data, medical coding, protocol deviations, and external data sources. - Manage MedDRA and WHODrug coding activities. - Support database lock activities and final data transfers for statistical analysis and regulatory submissions. Vendor and CRO Management - Manage bioanalytical vendors for PK assays and ensure appropriate data collection. - Provide oversight of CROs, EDC providers, specialty laboratories, and other external vendors. - Participate in vendor selection, RFP reviews, and vendor assessments. - Review vendor contracts, data transfer agreements, and service deliverables. - Monitor vendor performance, timelines, quality metrics, and issue resolution. Cross-Functional Collaboration - Partner with Biostatistics and Statistical Programming to support data review, SAP development, listings review, and submission readiness. - Collaborate with Clinical Operations, Clinical Pharmacology, Safety, Regulatory Affairs, and Medical teams to ensure accurate data collection and reporting. - Provide data management updates, risk assessments, and recommendations in study team meetings. - Support preparation and review of clinical study reports, tables, listings, and regulatory submission deliverables. Process Improvement and Compliance - Contribute to development and continuous improvement of Data Management processes, SOPs, standards, and best practices. - Ensure compliance with ICH-GCP, FDA regulations, CDISC/CDASH standards, GCDMP guidelines, and company procedures. - Support inspection readiness and participate in regulatory inspections and audits. - Mentor junior team members and contribute to team development. Required Education and Experience: - BS/BA in bioscience, engineering, computer science, medical training, or related field; MS/MA preferred. - Senior Manager: 6+ years (MS/MA) or 9+ years (BS/BA) of clinical data management experience in biotechnology, pharmaceutical, or CRO industry. - Associate Director: 9+ years (MS/MA) or 12+ years (BS/BA) of clinical data management experience in biotechnology, pharmaceutical, or CRO industry. - Experience leading data management from study start-up through database lock. - Strong vendor and CRO oversight experience. - Experience supporting regulatory submissions and inspection readiness. Preferred: - Management of PK trial data and clinical pharmacology experience. Additional Skills, Knowledge, and Abilities: - Deep understanding of clinical data management principles and industry standards. - Working knowledge of ICH-GCP, FDA regulations, 21 CFR Part 11, CDISC/CDASH, SDTM, MedDRA, and WHODrug. - Experience with EDC systems such as Medidata Rave or equivalent. - Experience with drug development and PK sample collection. - Strong understanding of external data integrations, reconciliation processes, and database lock procedures. - Strong project management, organizational, and problem-solving skills. - Ability to manage multiple priorities in a fast-paced environment.

🏢 Summary: The Director Clinical Data Management leads and oversees all clinical data management activities across multiple clinical trials, ensuring high-quality, inspection-ready data to support regulatory submissions and business objectives. This role sets data strategy, manages CROs and vendors, and drives risk-based quality and process excellence across Phase I–III programs. The position collaborates cross-functionally to deliver compliant data aligned with global regulatory standards. 🗂️ Requirements: BS/BA in Life Sciences, Engineering, Computer Science, Mathematics, Statistics or related field, 12+ years (MS) or 15+ years (BS) in clinical data management in biotech, pharma, or CRO, 5+ years of people management experience, Experience supporting Phase I–III clinical trials, Experience overseeing CROs and external data management vendors, Strong knowledge of CDISC standards, Strong knowledge of GCP and ICH Guidelines, Strong knowledge of FDA and global regulatory requirements, Experience with modern EDC systems (Medidata Rave, Veeva CDMS, Oracle or equivalent), Experience with risk-based quality management (RBQM) 📃 Skills: CDISC, GCP, ICH, FDA, EDC, Medidata, Rave, Veeva, Oracle, RBQM 🏢 Description: Position Summary: The Director Clinical Data Management provides strategic and operational leadership for all clinical data management activities across the clinical development portfolio. This individual serves as the functional leader for Data Management, responsible for establishing data strategy, overseeing external partners, driving process excellence, and ensuring the delivery of high-quality, inspection-ready clinical data that supports clinical development, regulatory submissions, and business objectives. Essential Duties and Responsibilities: Lead and oversee all clinical data management activities across multiple clinical studies and development programs. Develop and implement data management strategies that support clinical, regulatory, and business objectives. Provide leadership and oversight of CROs and technology vendors responsible for data management deliverables. Ensure quality, integrity, consistency, and timely availability of clinical trial data. Collaborate closely with Biostatistics, Statistical Programming, Clinical Operations, Clinical Development, Medical Monitoring, Regulatory Affairs, and Pharmacovigilance teams. Review and approve key study documentation including: Data Management Plans Edit Check Specifications CRF Design Data Review Plans Database Build and Validation Documentation Drive risk-based data review and quality management practices. Support regulatory inspections and audits. Contribute to submission readiness activities including NDA, BLA, MAA, and other global regulatory filings. Build scalable data management processes, standards, and SOPs as the organization grows. Mentor and develop internal team members and consultants. Required Education and Experience: BS/BA degree in Life Sciences, Engineering, Computer Science, Mathematics, Statistics, or related field; MS/MA degree preferred. 12+ (if MS/MA degree) or 15+ (if BS/BA degree) years of clinical data management experience within biotechnology, pharmaceutical, CRO, or related environments. 5+ years of people management experience. Demonstrated experience supporting Phase I–III clinical trials. Experience overseeing external data management vendors and CRO partnerships. Strong understanding of: CDISC standards GCP ICH Guidelines FDA and global regulatory requirements Experience with modern EDC systems such as Medidata Rave, Veeva CDMS, Oracle, or equivalent platforms. Additional Skills, Knowledge, Abilities: Experience with risk-based quality management (RBQM).

🏢 Summary: Senior commercial leadership role responsible for architecting and executing global and U.S. launch strategy for a lead biologic candidate in Hidradenitis Suppurativa. The position drives brand strategy, launch readiness, market access, and cross-functional alignment to ensure successful first product commercialization. This role combines strategic vision with hands-on execution in a fast-paced biotechnology environment. 🗂️ Requirements: Bachelor’s degree, 12+ years biotechnology, pharmaceutical, or healthcare industry experience, 5+ years leading launch planning or commercial operations, Experience leading at least one major pharmaceutical or biotechnology product launch, Experience managing cross-functional initiatives in a matrixed environment 📃 Skills: Commercialization, Launch, Forecasting, CompetitiveIntelligence, MarketAccess, HEOR, Regulatory, Biologics, Immunology, Dermatology, Pricing, Contracting, KPIs 🏢 Description: Position Summary: This individual will serve as the commercial architect for Avalo's first potential product launch. The successful candidate will be responsible for developing and executing global and U.S. launch readiness plans, shaping brand strategy, generating deep customer insights, building commercial capabilities, and partnering cross-functionally to maximize the value of the HS franchise. This highly visible leadership role requires a strategic thinker who can operate effectively in a fast-paced biotechnology environment while balancing long-term commercial vision with hands-on execution. The individual will work closely with Clinical Development, Medical Affairs, Market Access, Regulatory Affairs, Investor Relations, Business Development, and external partners to position Avalo for a successful commercialization and growth trajectory. Essential Duties and Responsibilities: Commercial Strategy & Brand Leadership Advance and lead the overall commercial strategy for abdakibart, Avalo's lead drug candidate, in Hidradenitis Suppurativa (HS). Build the brand vision, positioning, messaging, value proposition, and lifecycle strategy. Direct market assessment, forecasting, competitive intelligence, and commercial planning activities. Translate clinical and scientific data into differentiated customer-focused strategies. Identify market opportunities, risks, and competitive dynamics to inform business decisions. Serve as the commercial lead on cross-functional program teams. Manage external agency partners. Launch Excellence Build and execute comprehensive cross-functional launch readiness plans. Establish launch milestones, KPIs, governance structures, and performance tracking mechanisms. Lead pre-launch customer engagement and market shaping initiatives. Ensure organizational readiness across marketing, sales, market access, patient services, and operations. Develop launch scenarios and contingency plans to support evolving clinical and regulatory timelines. Customer Insights & Market Development Generate actionable insights from healthcare providers, patients, payers, advocacy groups, and key opinion leaders. Develop customer segmentation and targeting strategies. Establish strong relationships with external experts, advocacy organizations and HS stakeholders. Market Access & Value Strategy Partner closely with Market Access to develop payer, reimbursement, and value communication strategies. Support pricing, contracting, and access planning efforts. Ensure commercial strategies are aligned with payer expectations and patient access objectives. Cross-Functional Leadership Collaborate closely with Clinical Development and operations, HEOR, Medical Affairs, Regulatory Affairs, Manufacturing, and Supply Chain to ensure commercial perspectives are integrated throughout development. Partner with Medical Affairs to optimize scientific communication plans and publication strategies. Support investor and board communications regarding the commercial opportunity for abdakibart in HS and launch readiness plans. Represent commercial perspectives in governance and strategic planning discussions. Required Education and Experience: Bachelor's degree required; advanced degree (MBA, MPH, PharmD, MS, or PhD) preferred. 12+ years of biotechnology, pharmaceutical, or healthcare industry experience. 5+ years leading launch planning, launch excellence, commercial operations, new product planning, or strategic program management. Demonstrated success leading at least one major pharmaceutical or biotechnology product launch. Experience coordinating complex, cross-functional initiatives in a matrixed environment. Experience in dermatology and/or immunology/inflammation specialty products, preferred. Preferred Qualifications Experience launching biologics or specialty therapies. Understanding of HS, dermatology, immunology, or inflammatory disease markets. Experience within emerging biotechnology companies and first-launch organizations. Familiarity with global launch planning and commercialization frameworks.

🏢 Summary: The role focuses on ensuring GxP‑regulated digital systems, particularly LIMS and connected laboratory platforms, remain validated, compliant, and fit for purpose throughout their lifecycle. It combines hands‑on CSV validation, data integrity oversight, and system integration control with product ownership and stakeholder collaboration in Agile/DevOps environments. The position supports global validation, user adoption, and continuous improvement of regulated laboratory systems. 🗂️ Requirements: Bachelor’s or Master’s degree in Computer Science, Engineering or related field, Minimum 5 years of experience in product specialist or validation roles, Strong experience with GxP / CSV validation of laboratory or scientific software, Hands-on experience with ValGenesis and/or Azure DevOps, Knowledge of software development lifecycle in Agile/DevOps environments, Experience with validation lifecycle activities (IQ, OQ, PQ), Understanding of data integrity principles (ALCOA+), Experience validating system integrations and interfaces, Knowledge of role-based access control and electronic records/signatures compliance 📃 Skills: GxP, CSV, LIMS, SDMS, SAP, ValGenesis, Azure, DevOps, ALCOA+, IQ, OQ, PQ, ERP, Agile, RBAC 🏢 Description: At Bayer, we are committed to transparency, equal pay for equal work or work of equal value, and objective reward practices in line with EU and local regulations. The minimum annual gross compensation for this role is 20 240 PLN , with final pay determined based on objective factors such as experience, qualifications, scope of responsibility, and internal alignment. This position is eligible for variable pay components , such as performance‑based bonuses, awarded in accordance with the applicable employee group, role scope, and compensation structure. In addition, Bayer offers a competitive and holistic benefits package, including: - Medical care above statutory requirements - Flexible benefits supporting leisure, and well‑being/sports programs - Life, accident, and disability insurance through group coverage - Employer‑supported pension plans with regular company contributions - Home office allowance to support hybrid or remote work - Extra Paid Holidays Benefits may vary depending on country, role, and employment conditions. For Digital Hub Warsaw, we are looking for: Senior Product Specialist: As a Senior Product Specialist, you will ensure regulated digital products remain compliant, validated, and user-friendly throughout their lifecycle. You will combine GxP validation expertise, product enablement, and stakeholder collaboration to deliver high-quality solutions, particularly across LIMS and connected laboratory systems. YOUR TASKS AND RESPONSIBILITIES Validation & Compliance Lead GxP validation activities across the full system lifecycle (implementation → decommissioning). Plan and oversee IQ/OQ/PQ, ensuring systems remain in a validated state in Agile/DevOps environments. Manage validation deliverables (plans, risk assessments, testing, deviations, change control). Ensure data integrity (ALCOA+), audit trails, e-signatures, and access controls. Validate integrations with LIMS, SDMS, instruments, and ERP/SAP. Act as SME for validation and compliance topics . Product Adoption & Collaboration Drive user adoption through training, communication, and documentation. Align stakeholders across business, quality, and engineering. Coordinate UAT, acceptance criteria, and release readiness. Translate technical and compliance topics for diverse audiences. Use feedback and metrics to improve product performance and user experience . Leadership & Delivery Lead cross-functional initiatives and validation workstreams. Manage timelines, risks, and dependencies. Support continuous improvement and mentor junior team members. WHO YOU ARE: Required Qualifications Bachelor’s or Master’s degree in Computer Science, Engineering, Life Sciences, or related field. 5–7+ years of experience in product specialization, validation, or similar roles in regulated environments. Strong hands-on experience in GxP / CSV validation of scientific or laboratory software. Proven experience with validation tools such as ValGenesis and/or Azure DevOps. Strong understanding of software development lifecycle (SDLC) and Agile/DevOps methodologies. Demonstrated ability to lead cross-functional initiatives and manage complex projects. Excellent communication, stakeholder management, and influencing skills. Preferred Qualifications Experience with LIMS, SDMS, or SAP in regulated laboratory environments. Exposure to product development, backlog management, or product ownership concepts. Formal project management experience or certification. Experience working in global, multi-regional, or multi-platform environments. Ability to influence without formal authority and navigate complex stakeholder landscapes Please send your CV in English.

🏢 Summary: Remote Software Development Manager role leading a team of .NET developers in healthcare IT, with a strong focus on driving AI-assisted development practices using tools like Claude and GitHub Copilot. The position combines people management, technical leadership, software delivery oversight, and healthcare compliance responsibilities. Candidates must have deep .NET expertise, hands-on AI coding tool experience, and experience managing development teams in regulated environments. 🗂️ Requirements: 5+ years of .NET development experience, 2+ years in team lead, tech lead, or people management role, Hands-on experience with AI coding tools, Experience integrating AI tools into daily development workflows, Experience managing software delivery in healthcare or regulated industries, Strong communication skills with technical and non-technical stakeholders, Knowledge of healthcare IT security requirements, Ability to lead AI adoption initiatives, Experience with C#, Experience with ASP.NET, Experience with SQL Server 📃 Skills: .NET, C#, ASP.NET, SQL, SQLServer, Claude, GitHub, Copilot, HL7, HIPAA, PHI, LLM, SSRS, PowerBI 🏢 Description: REMOTE OPPORTUNITY for Oregon, Washington, and Idaho Residents ONLY Adaugeo Healthcare Solutions is seeking a Software Development Manager to lead the Application Development team — a team of six .NET developers building and maintaining the custom applications, integrations, and internal tooling that support AHS and its affiliated entities, Praxis Health and Interpath Laboratory. This is not a caretaker role. AHS is actively investing in AI-assisted development, and this manager will be expected to lead that transition — hands-on. The right candidate brings strong .NET technical depth, genuine experience using AI coding tools (including Claude) in their own development work, and the drive to accelerate what a six-person team can deliver by working smarter with AI. If you have been quietly building faster and better because of AI tools and you want to bring that mindset to a team, this role was written for you. AI Adoption Leadership - Model hands-on use of AI coding tools — including Claude and GitHub Copilot — in your own day-to-day work: code generation, review, refactoring, documentation, and problem-solving. - Develop and maintain team standards for AI-assisted development: when to use it, how to validate output, and how to incorporate AI tools into code review and QA processes. - Establish measurable velocity and quality benchmarks before and after AI tool adoption so the team can demonstrate concrete impact to leadership. - Stay current on the AI tooling landscape and bring forward recommendations on new tools, models, or workflows that could benefit the team. - Coach individual contributors on effective AI prompting, tool integration into their development environments, and building AI-native workflows into their daily practice. - Serve as the internal subject matter expert on AI-assisted .NET development, partnering with the Director of IT on broader AI adoption initiatives across AHS. People Leadership & Team Development - Provide direct management for six .NET developers, including performance reviews, goal-setting, career development, and day-to-day coaching. - Conduct regular 1:1s and team stand-ups; maintain clear visibility into individual workloads, blockers, and development goals. - Foster a culture of continuous improvement, technical craftsmanship, and psychological safety. - Identify training needs and create development paths that combine traditional .NET skills with emerging AI-augmented practices. Delivery & Project Execution - Own the application development backlog and release calendar, partnering with the Director of IT and business stakeholders to prioritize work. - Ensure projects are scoped, estimated, tracked, and delivered with clear communication and appropriate documentation. - Manage competing priorities across entities and escalate resourcing conflicts early and clearly. - Use AI tools to accelerate delivery planning, technical documentation, and sprint retrospectives. Technical Direction - Serve as a technical authority for the .NET application stack, guiding architectural decisions and code quality standards in partnership with senior developers. - Evaluate and recommend AI-native development approaches: code generation pipelines, AI-assisted testing, automated documentation, and LLM-integrated application features where appropriate. - Ensure all development practices meet healthcare IT security requirements, including HIPAA technical safeguards, PHI handling, audit trail design, and access control standards. - Drive consistency in development standards, code review practices, and QA processes across the team. Cross-Functional Partnership - Act as the primary IT liaison for clinical, laboratory, revenue cycle, and operational stakeholders requesting application development or changes. - Collaborate with the Infrastructure Manager and IT Support Manager on deployments, environment management, and production escalations. - Partner with the Director of IT on roadmap planning, capacity analysis, and resource strategy. Schedule The standard work hours are 8:00 AM to 5:00 PM PST, with flexibility as long as core hours (8:00 AM to 3:00 PM) are covered. Benefits - Medical, Dental, Vision with In-Network & Custom Network discounts - 401(K) with discretionary employer match - Paid Time Off - Free clinical diagnostic laboratory testing performed in house Qualifications Required - 5+ years of software development experience in .NET (C#, ASP.NET, SQL Server). - 2+ years in a team lead, tech lead, or people management role with direct reports. - Demonstrated, hands-on experience using AI coding tools — Claude, GitHub Copilot, or equivalent — in production development work. - Experience managing software delivery in a healthcare or regulated industry environment. - Strong communication skills; ability to translate technical work to non-technical clinical and operational stakeholders. Preferred - Experience with HL7 or clinical data exchange. - Familiarity with HIPAA technical safeguards and PHI handling requirements in software systems. - Experience building or integrating LLM-powered features into internal business applications. - Exposure to BI or reporting tooling (SSRS, Power BI). - Background supporting multi-entity or multi-site healthcare organizations. Physical Requirements Manual dexterity for office machine operation including computer operations, stooping, bending, mobility to complete errands, or sitting for extended periods of time. Stress can be triggered by multiple staff demands and deadlines.

🏢 Summary: Remote Software Development Manager role leading a team of .NET developers with a strong focus on AI-assisted development using tools like Claude and GitHub Copilot. The position combines hands-on technical leadership, people management, software delivery oversight, and healthcare IT compliance responsibilities. Candidates are expected to drive AI adoption, guide .NET architecture decisions, and manage development projects across healthcare-related business entities. 🗂️ Requirements: 5+ years of .NET software development experience, 2+ years in team lead, tech lead, or people management role, Hands-on experience with AI coding tools, Experience integrating AI tools into daily development workflows, Experience managing software delivery in healthcare or regulated environments, Strong knowledge of C#, ASP.NET, and SQL Server, Ability to lead AI-assisted development adoption, Strong communication with technical and non-technical stakeholders, Knowledge of healthcare IT security requirements, Ability to manage application development backlog and release planning 📃 Skills: .NET, C#, ASP.NET, SQL, SQLServer, Claude, GitHubCopilot, HL7, HIPAA, PHI, SSRS, PowerBI, LLM, AI 🏢 Description: REMOTE OPPORTUNITY for Oregon, Washington, and Idaho Residents ONLY Adaugeo Healthcare Solutions is seeking a Software Development Manager to lead the Application Development team — a team of six .NET developers building and maintaining the custom applications, integrations, and internal tooling that support AHS and its affiliated entities, Praxis Health and Interpath Laboratory. This is not a caretaker role. AHS is actively investing in AI-assisted development, and this manager will be expected to lead that transition — hands-on. The right candidate brings strong .NET technical depth, genuine experience using AI coding tools (including Claude) in their own development work, and the drive to accelerate what a six-person team can deliver by working smarter with AI. AI Adoption Leadership - Model hands-on use of AI coding tools — including Claude and GitHub Copilot — in day-to-day work: code generation, review, refactoring, documentation, and problem-solving. - Develop and maintain team standards for AI-assisted development. - Establish measurable velocity and quality benchmarks before and after AI tool adoption. - Stay current on the AI tooling landscape and recommend new tools, models, or workflows. - Coach contributors on effective AI prompting and AI-native workflows. - Serve as the internal subject matter expert on AI-assisted .NET development. People Leadership & Team Development - Provide direct management for six .NET developers, including performance reviews, goal-setting, career development, and coaching. - Conduct regular 1:1s and team stand-ups. - Foster a culture of continuous improvement and technical craftsmanship. - Identify training needs and create development paths combining .NET and AI-augmented practices. Delivery & Project Execution - Own the application development backlog and release calendar. - Ensure projects are scoped, estimated, tracked, and delivered with documentation. - Manage competing priorities and escalate resourcing conflicts. - Use AI tools to accelerate delivery planning, documentation, and retrospectives. Technical Direction - Serve as a technical authority for the .NET application stack. - Evaluate and recommend AI-native development approaches. - Ensure development practices meet healthcare IT security requirements, including HIPAA safeguards, PHI handling, audit trail design, and access controls. - Drive consistency in development standards, code reviews, and QA processes. Cross-Functional Partnership - Act as the primary IT liaison for clinical, laboratory, revenue cycle, and operational stakeholders. - Collaborate on deployments, environment management, and production escalations. - Partner on roadmap planning, capacity analysis, and resource strategy. Schedule The standard work hours are 8:00 AM to 5:00 PM PST, with flexibility as long as core hours (8:00 AM to 3:00 PM) are covered. Benefits - Medical, Dental, Vision with In-Network & Custom Network discounts - 401(K) with discretionary employer match - Paid Time Off - Free clinical diagnostic laboratory testing performed in house Qualifications Required - 5+ years of software development experience in .NET (C#, ASP.NET, SQL Server). - 2+ years in a team lead, tech lead, or people management role with direct reports. - Demonstrated hands-on experience using AI coding tools such as Claude or GitHub Copilot in production development work. - Clear understanding of AI-assisted development trends and adoption strategies. - Experience managing software delivery in a healthcare or regulated industry environment. - Strong communication skills. Preferred - Experience with HL7 or clinical data exchange. - Familiarity with HIPAA safeguards and PHI handling requirements. - Experience building or integrating LLM-powered features into business applications. - Exposure to BI or reporting tooling such as SSRS or Power BI. - Background supporting multi-entity or multi-site healthcare organizations. Physical Requirements - Manual dexterity for office machine operation including computer operations. - Mobility for office-related tasks and extended sitting periods. - Ability to manage stress from multiple staff demands and deadlines.

🏢 Summary: Remote Software Development Manager role leading a team of .NET developers with a strong focus on AI-assisted development practices using tools like Claude and GitHub Copilot. The position combines hands-on technical leadership, people management, software delivery oversight, and healthcare IT compliance responsibilities. Candidates must have deep .NET expertise, leadership experience, and proven use of AI coding tools in production environments. 🗂️ Requirements: 5+ years of .NET development experience, 2+ years in team lead or people management role, Experience with C#, Experience with ASP.NET, Experience with SQL Server, Hands-on use of AI coding tools, Experience with Claude, Experience with GitHub Copilot, Experience managing software delivery, Experience in healthcare or regulated industry, Knowledge of healthcare IT security requirements, Strong communication skills 📃 Skills: .NET, C#, ASP.NET, SQL, SQLServer, Claude, GitHubCopilot, AI, HL7, HIPAA, PHI, SSRS, PowerBI, LLM 🏢 Description: REMOTE OPPORTUNITY for Oregon, Washington, and Idaho Residents ONLY Adaugeo Healthcare Solutions is seeking a Software Development Manager to lead the Application Development team — a team of six .NET developers building and maintaining the custom applications, integrations, and internal tooling that support AHS and its affiliated entities, Praxis Health and Interpath Laboratory. This is not a caretaker role. AHS is actively investing in AI-assisted development, and this manager will be expected to lead that transition — hands-on. The right candidate brings strong .NET technical depth, genuine experience using AI coding tools (including Claude) in their own development work, and the drive to accelerate what a six-person team can deliver by working smarter with AI. AI Adoption Leadership - Model hands-on use of AI coding tools — including Claude and GitHub Copilot — in day-to-day work: code generation, review, refactoring, documentation, and problem-solving. - Develop and maintain team standards for AI-assisted development. - Establish measurable velocity and quality benchmarks before and after AI tool adoption. - Stay current on the AI tooling landscape and recommend new tools, models, or workflows. - Coach contributors on effective AI prompting and AI-native workflows. - Serve as the internal subject matter expert on AI-assisted .NET development. People Leadership & Team Development - Provide direct management for six .NET developers, including performance reviews, goal-setting, career development, and coaching. - Conduct regular 1:1s and team stand-ups. - Foster a culture of continuous improvement and technical craftsmanship. - Identify training needs and create development paths. Delivery & Project Execution - Own the application development backlog and release calendar. - Ensure projects are scoped, estimated, tracked, and delivered with documentation. - Manage competing priorities and escalate resourcing conflicts. - Use AI tools to accelerate delivery planning and retrospectives. Technical Direction - Serve as a technical authority for the .NET application stack. - Evaluate and recommend AI-native development approaches. - Ensure development practices meet healthcare IT security requirements, including HIPAA safeguards, PHI handling, audit trails, and access control standards. - Drive consistency in development standards and QA processes. Cross-Functional Partnership - Act as the primary IT liaison for clinical, laboratory, revenue cycle, and operational stakeholders. - Collaborate on deployments, environment management, and production escalations. - Partner on roadmap planning, capacity analysis, and resource strategy. Schedule The standard work hours are 8:00 AM to 5:00 PM PST, with flexibility as long as core hours (8:00 AM to 3:00 PM) are covered. Benefits - Medical, Dental, Vision with In-Network & Custom Network discounts - 401(K) with discretionary employer match - Paid Time Off - Free clinical diagnostic laboratory testing performed in house Qualifications Required - 5+ years of software development experience in .NET (C#, ASP.NET, SQL Server) - 2+ years in a team lead, tech lead, or people management role with direct reports - Demonstrated hands-on experience using AI coding tools such as Claude or GitHub Copilot in production development work - Clear understanding of AI-assisted development practices - Experience managing software delivery in a healthcare or regulated industry environment - Strong communication skills Preferred - Experience with HL7 or clinical data exchange - Familiarity with HIPAA technical safeguards and PHI handling requirements - Experience building or integrating LLM-powered features - Exposure to SSRS or Power BI - Background supporting multi-entity or multi-site healthcare organizations Physical Requirements Manual dexterity for office machine operation including computer operations, stooping, bending, mobility to complete errands, or sitting for extended periods of time. Stress can be triggered by multiple staff demands and deadlines.

🏢 Summary: Remote Software Development Manager role leading a .NET development team with a strong focus on AI-assisted development using tools like Claude and GitHub Copilot. The position combines hands-on technical leadership, people management, healthcare software delivery, and AI adoption strategy across custom applications and integrations. Candidates must have deep .NET expertise, experience managing development teams, and practical use of AI coding tools in production environments. 🗂️ Requirements: 5+ years experience with .NET development, 2+ years experience in team lead or management role, Hands-on use of AI coding tools in production workflows, Experience with C#, Experience with ASP.NET, Experience with SQL Server, Experience managing software delivery in regulated or healthcare environments, Knowledge of healthcare IT security and HIPAA safeguards, Ability to lead AI-assisted development adoption, Strong technical communication skills 📃 Skills: .NET, C#, ASP.NET, SQL, SQLServer, Claude, GitHubCopilot, AI, LLM, HL7, HIPAA, PHI, SSRS, PowerBI 🏢 Description: Adaugeo Healthcare Solutions is seeking a Software Development Manager to lead the Application Development team — a team of six .NET developers building and maintaining custom applications, integrations, and internal tooling that support affiliated healthcare entities. This role is heavily focused on driving AI-assisted development adoption within the engineering team. Quick Facts - Remote opportunity for Oregon, Washington, and Idaho residents only - Standard work hours: 8:00 AM to 5:00 PM PST with flexibility as long as core hours are covered AI Adoption Leadership - Model hands-on use of AI coding tools including Claude and GitHub Copilot in day-to-day development work - Develop and maintain standards for AI-assisted development workflows and validation - Establish measurable velocity and quality benchmarks related to AI tool adoption - Stay current on AI tooling and recommend improvements to workflows and tools - Coach developers on AI prompting and AI-native workflows - Serve as the internal subject matter expert on AI-assisted .NET development People Leadership & Team Development - Manage six .NET developers including reviews, coaching, and career development - Conduct regular 1:1 meetings and team stand-ups - Foster continuous improvement and experimentation with AI workflows - Identify training needs and support development in AI-augmented engineering practices Delivery & Project Execution - Own the application development backlog and release calendar - Scope, estimate, track, and deliver projects with clear communication and documentation - Manage competing priorities and escalate resourcing conflicts - Use AI tools to accelerate planning, documentation, and retrospectives Technical Direction - Guide architectural decisions and code quality standards for the .NET application stack - Evaluate AI-native development approaches including automated documentation and AI-assisted testing - Ensure compliance with healthcare IT security requirements including HIPAA safeguards, PHI handling, audit trails, and access controls - Drive consistency in development standards and QA processes Cross-Functional Partnership - Act as the primary IT liaison for operational and clinical stakeholders - Collaborate on deployments, environment management, and production escalations - Partner on roadmap planning, capacity analysis, and resource strategy Benefits - Medical, Dental, Vision benefits - 401(K) with discretionary employer match - Paid Time Off - Free clinical diagnostic laboratory testing performed in house Qualifications Required - 5+ years of software development experience in .NET, C#, ASP.NET, and SQL Server - 2+ years in a team lead, tech lead, or people management role with direct reports - Demonstrated hands-on experience using AI coding tools such as Claude or GitHub Copilot in production development - Strong understanding of AI-assisted development practices and adoption strategy - Experience managing software delivery in healthcare or regulated industries - Strong communication skills with technical and non-technical stakeholders Preferred - Experience with HL7 or clinical data exchange - Familiarity with HIPAA safeguards and PHI handling requirements - Experience integrating LLM-powered features into applications - Exposure to SSRS or Power BI - Experience supporting multi-entity healthcare organizations Physical Requirements - Manual dexterity for computer and office equipment operation - Ability to sit for extended periods and perform basic mobility tasks - Ability to manage stress from deadlines and multiple staff demands

🏢 Summary: The Bioinformatics Scientist role supports NIH research by independently designing and implementing advanced computational analyses for high-dimensional omics data. The position focuses on statistical genomics, machine learning, and multi-omics integration to generate biologically meaningful insights. The scientist develops scalable pipelines, custom software, and reproducible workflows while collaborating with interdisciplinary research teams. 🗂️ Requirements: Ph.D. in Bioinformatics, Computational Biology, Genomics, Data Science, Biostatistics, Computer Science, Biomedical Engineering or related quantitative field (Master’s with relevant experience acceptable), Minimum three years of relevant research experience, Experience in machine learning or advanced statistical modeling for high-dimensional biological data, Expertise in next-generation sequencing data analysis, Experience with multi-omics data integration, Proficiency in programming for bioinformatics analysis, Experience developing and maintaining analytical pipelines, Ability to work with large-scale datasets, Experience establishing reproducible workflows and documentation practices 📃 Skills: R, Python, MATLAB, Linux, Unix, Java, Shell, Perl, Bash, SAS, Git, Docker, Singularity, Apptainer, HPC, RNA-Seq, ChIP-Seq, miRNA-Seq, GWAS, Microarray, MachineLearning, DeepLearning, Multiomics, Statistics, Genomics, Transcriptomics, Epigenomics, Proteomics, DataVisualization, WorkflowManagement, Cloud 🏢 Description: Axle is seeking a Bioinformatics Scientist to support research activities at the National Institutes of Health (NIH) in Research Triangle Park, NC. Benefits We Offer: - 100% Medical, Dental & Vision Coverage for Employees - Paid Time Off and Paid Holidays - 401K match up to 5% - Educational Benefits for Career Growth - Employee Referral Bonus - Flexible Spending Accounts: - Healthcare (FSA) - Parking Reimbursement Account (PRK) - Dependent Care Assistant Program (DCAP) - Transportation Reimbursement Account (TRN) Position Information: This position independently provides bioinformatics and data science support to advance the institute's operational and research objectives. The role requires expertise in statistical genomics, machine learning, and scalable analysis and integration of high-dimensional omics data, applying AI-driven methods to generate biologically meaningful insights. Additional Qualifications: - Ph.D. preferred (or Master's) in Bioinformatics, Computational Biology, Genomics, Data Science, Biostatistics, Computer Science, Biomedical Engineering, or a closely related quantitative field - Three years of experience in a relevant discipline - Demonstrated training or experience in machine learning, artificial intelligence, or advanced statistical modeling applied to high-dimensional biological data Software: - R - Python - MATLAB - Linux - Unix - Java - Shell - PERL - Bash - SAS - HPC - Git - Docker / Singularity / Apptainer - Workflow management tools Core Technical Areas: - Next-generation sequencing data analysis (Bulk RNA-Sequencing, Single Cell RNA-Sequencing) - Genome-wide association studies - Microarray data analysis - Multi-omics analysis and integration - Pipeline development - Machine learning and deep learning - Representation learning for omics data - Cloud platforms - Reproducible research practices - Data visualization Deliverables and Responsibilities: - Design analytical strategies and resolve scientific or technical challenges - Analyze and interpret high-throughput biological data - Develop and maintain custom analytical software, scripts, and computational pipelines - Establish reproducible workflows and standard operating procedures (SOPs) - Optimize analytical pipelines for multi-omics datasets - Perform preprocessing, quality control, integration, clustering, and differential expression analysis of single-cell datasets - Conduct analyses on NextGen sequencing data including ChIP-Seq, RNA-Seq, miRNA-Seq and related platforms - Perform genomic platform analysis including expression, exon, tiling, and promoter arrays - Apply machine learning approaches to integrate large-scale, complex multi-omic data - Develop computational infrastructure resources for large and complex datasets - Provide statistical support and devise novel analytical methods - Prepare scientific reports, publication-quality figures, and manuscripts - Present findings at meetings, seminars, and conferences - Train staff and provide technical support for bioinformatics tools and pipelines - Collaborate with interdisciplinary teams to design experiments and interpret results - Maintain detailed documentation and reproducible data analysis practices