Senior Global Medical Affairs Lead CVRM

Quick Facts

• Reporting line: Medical Head
• Role focus: Senior Global Medical Affairs Lead (Cardiovascular/CVRM therapy area)
• Work model: Office-based 3 days/week (Gaithersburg, MD or Boston, MA)

Description

This role is a highly experienced Medical Affairs leadership position that develops and leads global medical strategies within the CVRM therapy area. It guides cross-functional and cross-regional teams to deliver ambitious enterprise-wide goals by shaping global medical agendas through Global Medical Team, Global Product Team, and Disease Area Team leadership. The role drives evidence generation and medical change initiatives, navigates health systems, and ensures medical science leadership externally and internally through strategic partnerships and world-class evidence.

Expectations of a Senior GMAL

Strategy & Transformation

• Design and lead implementation of product and disease area strategies at a global level
• Deliver practice change initiatives informed by healthcare system pathways, regulatory landscapes, market access, and competitive dynamics
• Use digital proficiency to identify data-driven opportunities supporting launch and life-cycle management

Medical Evidence Leadership

• Own evidence generation strategy across advanced clinical research, interventional trials (Phases 2–4), and real-world evidence (RWE)
• Shape and drive clinical trials, registries, and RWE studies aligned with brand, access, and practice-changing objectives
• Optimize, communicate, and roll out data across scientific platforms for regulatory, payer, and provider needs

Advanced Scientific & Digital Engagement

• Combine scientific expertise with digital acumen to transform evidence communication and personalize stakeholder engagement
• Use digital health tools, advanced analytics, and data platforms to enhance patient outcomes
• Craft compliant, accurate scientific narratives and disseminate evidence digitally

Guiding and Influencing Stakeholders

• Build relationships across the healthcare ecosystem (global/regional KOLs, societies, regulators, payers, patient organizations, digital innovators, health systems)
• Mobilize support for medical strategy, evidence generation, and healthcare change initiatives
• Mentor and guide cross-functional teams

Regulatory Insight & Compliance

• Ensure clinical trial and evidence generation initiatives are designed for scientific and regulatory success
• Anticipate evolving regulatory and payer evidence requirements
• Ensure high-quality, compliant data generation and communication

Essential Requirements

• Master’s degree (or higher) with at least 5 years of pharmaceutical industry experience (Medical, Marketing, R&D, Market Access) OR extensive health system experience (clinical, pharmacy, pathway design, etc.)
• Demonstrated leadership in complex, global healthcare environments
• Experience leading franchise/therapeutic area business in key markets and driving brand performance
• Experience managing large, diverse teams, including global launch of major products
• Expertise in healthcare system pathways, regulatory landscapes, market-shaping, and external stakeholder engagement
• Track record building internal/external networks, collaborating across geographies and matrix teams, and mentoring junior colleagues/peers
• Digital proficiency leveraging digital health tools and data platforms for evidence generation and communication
• Deep understanding of patient care pathways, evolving treatment protocols, scientific literature, and healthcare transformation approaches
• Ability to guide, influence, and align diverse stakeholders (thought leaders, regulators, patient groups, payers)

Desirable Qualifications

• Doctoral-level degree (MD, PhD, PharmD)
• Recognized therapeutic area expertise (clinical practice, research leadership, or external engagement)
• Advanced experience designing, leading, and interpreting clinical research programs (Ph2–Ph4 trials and practice-changing RWE)
• Experience beyond Medical Affairs (e.g., Marketing, R&D, Market Access)
• Long-standing relationships with global KOLs, societies, regulators, digital health partners, and innovative healthcare organisations
• Track record launching new products/indications in multiple markets (US, China, EU) and executing global medical strategies

Benefits (Summary)

• Qualified retirement program (401(k) plan)
• Paid vacation and holidays
• Paid leaves
• Health benefits: medical, prescription drug, dental, vision
• Short-term incentive bonus opportunity
• Equity-based long-term incentive program eligibility (salaried roles)
• Retirement contribution eligibility (hourly roles)
• Commission eligibility (sales roles)
• Overtime pay for qualifying overtime hours for hourly and salaried non-exempt employees
• At-will position; base pay and discretionary compensation programs may be modified based on performance, department/team results, and market factors